Bilberry/red grape juice decreases plasma biomarkers of inflammation and tissue damage in aged men with subjective memory impairment –a randomized clinical trial | BMC Nutrition

[ad_1]

  • 1.

    Reisberg B, Gauthier S. Current evidence for subjective cognitive impairment (SCI) as the pre-mild cognitive impairment (MCI) stage of subsequently manifest Alzheimer’s disease. Int Psychogeriatr. 2008;20(1):1–16. https://doi.org/10.1017/S1041610207006412.

    Article 
    PubMed 

    Google Scholar
     

  • 2.

    Reisberg B, Prichep L, Mosconi L, John ER, Glodzik-Sobanska L, Boksay I, et al. The pre-mild cognitive impairment, subjective cognitive impairment stage of Alzheimer’s disease. Alzheimers Dement. 2008;4(1 Suppl 1):S98–S108. https://doi.org/10.1016/j.jalz.2007.11.017.

    Article 
    PubMed 

    Google Scholar
     

  • 3.

    Gauthier S, Reisberg B, Zaudig M, Petersen RC, Ritchie K, Broich K, et al. Mild cognitive impairment. Lancet. 2006;367(9518):1262–70. https://doi.org/10.1016/S0140-6736(06)68542-5.

    Article 
    PubMed 

    Google Scholar
     

  • 4.

    Feldman HH, Jacova C. Mild cognitive impairment. Am J Geriatr Psychiatry. 2005;13(8):645–55. https://doi.org/10.1097/00019442-200508000-00003.

    Article 
    PubMed 

    Google Scholar
     

  • 5.

    Gjøra L, Strand BH, Bergh S, Borza T, Brækhus A, Engedal K, et al. Current and future prevalence estimates of mild cognitive impairment, dementia, and its subtypes in a population-based sample of people 70 years and older in Norway: the HUNT study. J Alzheimers Dis. 2021;79(3):1213–26. https://doi.org/10.3233/JAD-201275.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 6.

    Scheltens P, Blennow K, Breteler MM, de Strooper B, Frisoni GB, Salloway S, et al. Alzheimer’s disease. Lancet. 2016;388(10043):505–17. https://doi.org/10.1016/S0140-6736(15)01124-1.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 7.

    Lovell MA, Markesbery WR. Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer’s disease. Nucleic Acids Res. 2007;35(22):7497–504. https://doi.org/10.1093/nar/gkm821.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 8.

    Loef M, Walach H. Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging. 2012;16(7):626–30. https://doi.org/10.1007/s12603-012-0097-x.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 9.

    Andrade S, Ramalho MJ, Loureiro JA, Pereira MDC. Natural Compounds for Alzheimer’s Disease Therapy: A Systematic Review of Preclinical and Clinical Studies. Int J Mol Sci. 2019;20:92313. https://doi.org/10.3390/ijms20092313.

    CAS 
    Article 

    Google Scholar
     

  • 10.

    Travica N, D’Cunha NM, Naumovski N, Kent K, Mellor DD, Firth J, et al. The effect of blueberry interventions on cognitive performance and mood: a systematic review of randomized controlled trials. Brain Behav Immun. 2020;85:96–105. https://doi.org/10.1016/j.bbi.2019.04.001.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 11.

    Nurk E, Refsum H, Drevon CA, Tell GS, Nygaard HA, Engedal K, et al. Intake of flavonoid-rich wine, tea, and chocolate by elderly men and women is associated with better cognitive test performance. J Nutr. 2009;139(1):120–7. https://doi.org/10.3945/jn.108.095182.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 12.

    Bickford PC, Gould T, Briederick L, Chadman K, Pollock A, Young D, et al. Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Res. 2000;866(1–2):211–7. https://doi.org/10.1016/S0006-8993(00)02280-0.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 13.

    Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, et al. Mitophagy inhibits amyloid-beta and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease. Nat Neurosci. 2019;22(3):401–12. https://doi.org/10.1038/s41593-018-0332-9.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 14.

    McGuire SO, Sortwell CE, Shukitt-Hale B, Joseph JA, Hejna MJ, Collier TJ. Dietary supplementation with blueberry extract improves survival of transplanted dopamine neurons. Nutr Neurosci. 2006;9(5–6):251–8. https://doi.org/10.1080/10284150601086134.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 15.

    Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, et al. Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutr Neurosci. 2003;6(3):153–62. https://doi.org/10.1080/1028415031000111282.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 16.

    Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 2006;5(6):493–506. https://doi.org/10.1038/nrd2060.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 17.

    Pearson KJ, Baur JA, Lewis KN, Peshkin L, Price NL, Labinskyy N, et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell Metab. 2008;8(2):157–68. https://doi.org/10.1016/j.cmet.2008.06.011.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 18.

    Park YK, Kim JS, Kang MH. Concord grape juice supplementation reduces blood pressure in Korean hypertensive men: double-blind, placebo controlled intervention trial. Biofactors. 2004;22(1–4):145–7. https://doi.org/10.1002/biof.5520220128.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 19.

    Park YK, Lee SH, Park E, Kim JS, Kang MH. Changes in antioxidant status, blood pressure, and lymphocyte DNA damage from grape juice supplementation. Ann N Y Acad Sci. 2009;1171:385–90, 1. https://doi.org/10.1111/j.1749-6632.2009.04907.x.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 20.

    Karlsen A, Paur I, Bohn SK, Sakhi AK, Borge GI, Serafini M, et al. Bilberry juice modulates plasma concentration of NF-kappaB related inflammatory markers in subjects at increased risk of CVD. Eur J Nutr. 2010;49(6):345–55. https://doi.org/10.1007/s00394-010-0092-0.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 21.

    Karlsen A, Retterstol L, Laake P, Paur I, Kjolsrud-Bohn S, Sandvik L, et al. Anthocyanins inhibit nuclear factor-kappaB activation in monocytes and reduce plasma concentrations of pro-inflammatory mediators in healthy adults. J Nutr. 2007;137(8):1951–4. https://doi.org/10.1093/jn/137.8.1951.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 22.

    Habanova M, Saraiva JA, Haban M, Schwarzova M, Chlebo P, Predna L, et al. Intake of bilberries (Vaccinium myrtillus L.) reduced risk factors for cardiovascular disease by inducing favorable changes in lipoprotein profiles. Nutr Res. 2016;36(12):1415–22. https://doi.org/10.1016/j.nutres.2016.11.010.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 23.

    de Mello VD, Lankinen MA, Lindström J, Puupponen-Pimiä R, Laaksonen DE, Pihlajamäki J, et al. Fasting serum hippuric acid is elevated after bilberry (Vaccinium myrtillus) consumption and associates with improvement of fasting glucose levels and insulin secretion in persons at high risk of developing type 2 diabetes. Mol Nutr Food Res. 2017;61:9. https://doi.org/10.1002/mnfr.201700019.

    CAS 
    Article 

    Google Scholar
     

  • 24.

    Tjelle TE, Holtung L, Bøhn SK, Aaby K, Thoresen M, Wiik SÅ, et al. Polyphenol-rich juices reduce blood pressure measures in a randomised controlled trial in high normal and hypertensive volunteers. Br J Nutr. 2015;114(7):1054–63. https://doi.org/10.1017/S0007114515000562.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 25.

    Biedermann L, Mwinyi J, Scharl M, Frei P, Zeitz J, Kullak-Ublick GA, et al. Bilberry ingestion improves disease activity in mild to moderate ulcerative colitis – an open pilot study. J Crohn’s Colitis. 2013;7(4):271–9. https://doi.org/10.1016/j.crohns.2012.07.010.

    Article 

    Google Scholar
     

  • 26.

    Lehtonen HM, Suomela JP, Tahvonen R, Yang B, Venojärvi M, Viikari J, et al. Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women. Eur J Clin Nutr. 2011;65(3):394–401. https://doi.org/10.1038/ejcn.2010.268.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 27.

    Silva S, Costa EM, Veiga M, Morais RM, Calhau C, Pintado M. Health promoting properties of blueberries: a review. Crit Rev Food Sci Nutr. 2020;60(2):181–200. https://doi.org/10.1080/10408398.2018.1518895.

    Article 
    PubMed 

    Google Scholar
     

  • 28.

    Fray PJ, Robbins TW. CANTAB battery: proposed utility in neurotoxicology. Neurotoxicol Teratol. 1996;18(4):499–504. https://doi.org/10.1016/0892-0362(96)00027-X.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 29.

    Krikorian R, Nash TA, Shidler MD, Shukitt-Hale B, Joseph JA. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr. 2010;103(5):730–4. https://doi.org/10.1017/S0007114509992364.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 30.

    Lamport DJ, Lawton CL, Merat N, Jamson H, Myrissa K, Hofman D, et al. Concord grape juice, cognitive function, and driving performance: a 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children. Am J Clin Nutr. 2016;103(3):775–83. https://doi.org/10.3945/ajcn.115.114553.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 31.

    Krikorian R, Shidler MD, Nash TA, Kalt W, Vinqvist-Tymchuk MR, Shukitt-Hale B, et al. Blueberry supplementation improves memory in older adults. J Agric Food Chem. 2010;58(7):3996–4000. https://doi.org/10.1021/jf9029332.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 32.

    Bensalem J, Dudonné S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, et al. Polyphenols from grape and blueberry improve episodic memory in healthy elderly with lower level of memory performance: a Bicentric double-blind, randomized, placebo-controlled clinical study. J Gerontol A Biol Sci Med Sci. 2019;74(7):996–1007. https://doi.org/10.1093/gerona/gly166.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 33.

    Engedal K, Haugen P, Gilje K, Laake P. Efficacy of short mental tests in the detection of mental impairment in old age. Compr Gerontol A. 1988;2(2):87–93.

    CAS 
    PubMed 

    Google Scholar
     

  • 34.

    Carlsen MH, Lillegaard IT, Karlsen A, Blomhoff R, Drevon CA, Andersen LF. Evaluation of energy and dietary intake estimates from a food frequency questionnaire using independent energy expenditure measurement and weighed food records. Nutr J. 2010;9(1):37. https://doi.org/10.1186/1475-2891-9-37.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 35.

    Egerhazi A, Berecz R, Bartok E, Degrell I. Automated neuropsychological test battery (CANTAB) in mild cognitive impairment and in Alzheimer’s disease. Prog Neuro-Psychopharmacol Biol Psychiatry. 2007;31(3):746–51. https://doi.org/10.1016/j.pnpbp.2007.01.011.

    Article 

    Google Scholar
     

  • 36.

    Matthews C, Kløve H. Instruction manual for the adult neuropsychology test battery. Wisconsin: University of Wisconsin Medical School; 1964.


    Google Scholar
     

  • 37.

    Kløve H. CLINICAL NEUROPSYCHOLOGY. Med Clin North Am. 1963;47:1647–58, 6. https://doi.org/10.1016/S0025-7125(16)33515-5.

    Article 
    PubMed 

    Google Scholar
     

  • 38.

    Lafayette: Grooved Pegboard: User’s Manual. IN: Lafayette Instrument Company. 2003.


    Google Scholar
     

  • 39.

    Bastani NE, Gundersen TE, Blomhoff R. Determination of 8-epi PGF(2alpha) concentrations as a biomarker of oxidative stress using triple-stage liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2009;23(18):2885–90. https://doi.org/10.1002/rcm.4197.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 40.

    Bohn SK, Myhrstad MC, Thoresen M, Holden M, Karlsen A, Tunheim SH, et al. Blood cell gene expression associated with cellular stress defense is modulated by antioxidant-rich food in a randomised controlled clinical trial of male smokers. BMC Med. 2010;8(54):1. https://doi.org/10.1186/1741-7015-8-54.

    CAS 
    Article 

    Google Scholar
     

  • 41.

    Erlund I, Alfthan G, Siren H, Ariniemi K, Aro A. Validated method for the quantitation of quercetin from human plasma using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Sci Appl. 1999;727(1–2):179–89. https://doi.org/10.1016/S0378-4347(99)00049-3.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 42.

    Kilkkinen A, Erlund I, Virtanen MJ, Alfthan G, Ariniemi K, Virtamo J. Serum enterolactone concentration and the risk of coronary heart disease in a case-cohort study of Finnish male smokers. Am J Epidemiol. 2006;163(8):687–93. https://doi.org/10.1093/aje/kwj080.

    Article 
    PubMed 

    Google Scholar
     

  • 43.

    Oikarinen SI, Erlund I, Mutanen M. Tumour formation in multiple intestinal neoplasia (ApcMin/+) mice fed with filtered or unfiltered coffee. Food Nutr Res. 2007;51:167–73, 4. https://doi.org/10.1080/17482970701757119.

    Article 

    Google Scholar
     

  • 44.

    Lamport DJ, Dye L, Wightman JD, Lawton CL. The effects of flavonoid and other polyphenol consumption on cognitive performance: a systematic research review of human experimental and epidemiological studies. Nutrition and Aging. 2012;1(1):5–25. https://doi.org/10.3233/NUA-2012-0002.

    Article 

    Google Scholar
     

  • 45.

    Boespflug EL, Eliassen JC, Dudley JA, Shidler MD, Kalt W, Summer SS, et al. Enhanced neural activation with blueberry supplementation in mild cognitive impairment. Nutr Neurosci. 2018;21(4):297–305. https://doi.org/10.1080/1028415X.2017.1287833.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 46.

    Kolehmainen M, Mykkänen O, Kirjavainen PV, Leppänen T, Moilanen E, Adriaens M, et al. Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome. Mol Nutr Food Res. 2012;56(10):1501–10. https://doi.org/10.1002/mnfr.201200195.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 47.

    Newcombe EA, Camats-Perna J, Silva ML, Valmas N, Huat TJ, Medeiros R. Inflammation: the link between comorbidities, genetics, and Alzheimer’s disease. J Neuroinflammation. 2018;15(1):276. https://doi.org/10.1186/s12974-018-1313-3.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 48.

    Trapero I, Cauli O. Interleukin 6 and cognitive dysfunction. Metab Brain Dis. 2014;29(3):593–608. https://doi.org/10.1007/s11011-014-9551-2.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 49.

    Angelopoulos P, Agouridaki H, Vaiopoulos H, Siskou E, Doutsou K, Costa V, et al. Cytokines in Alzheimer’s disease and vascular dementia. Int J Neurosci. 2008;118(12):1659–72. https://doi.org/10.1080/00207450701392068.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 50.

    Baranowska-Bik A, Bik W, Wolinska-Witort E, Martynska L, Chmielowska M, Barcikowska M, et al. Plasma beta amyloid and cytokine profile in women with Alzheimer’s disease. Neuro Endocrinol Lett. 2008;29(1):75–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 51.

    Lee KS, Chung JH, Choi TK, Suh SY, Oh BH, Hong CH. Peripheral cytokines and chemokines in Alzheimer’s disease. Dement Geriatr Cogn Disord. 2009;28(4):281–7. https://doi.org/10.1159/000245156.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 52.

    Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, et al. Classification and prediction of clinical Alzheimer’s diagnosis based on plasma signaling proteins. Nat Med. 2007;13(11):1359–62. https://doi.org/10.1038/nm1653.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 53.

    Smits HA, Rijsmus A, van Loon JH, Wat JW, Verhoef J, Boven LA, et al. Amyloid-beta-induced chemokine production in primary human macrophages and astrocytes. J Neuroimmunol. 2002;127(1–2):160–8. https://doi.org/10.1016/S0165-5728(02)00112-1.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 54.

    Proescholdt MA, Jacobson S, Tresser N, Oldfield EH, Merrill MJ. Vascular endothelial growth factor is expressed in multiple sclerosis plaques and can induce inflammatory lesions in experimental allergic encephalomyelitis rats. J Neuropathol Exp Neurol. 2002;61(10):914–25. https://doi.org/10.1093/jnen/61.10.914.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 55.

    Strle K, Zhou JH, Shen WH, Broussard SR, Johnson RW, Freund GG, et al. Interleukin-10 in the brain. Crit Rev Immunol. 2001;21(5):427–49. https://doi.org/10.1615/CritRevImmunol.v21.i5.20.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 56.

    Kumar A, Naidu PS, Seghal N, Padi SSV. Neuroprotective effects of resveratrol against Intracerebroventricular colchicine-induced cognitive impairment and oxidative stress in rats. Pharmacology. 2007;79(1):17–26. https://doi.org/10.1159/000097511.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 57.

    Goulart M, Pisamiglio DS, MÖller GB, Dani C, Alves FD, Bock PM, et al. Effects of grape juice consumption on muscle fatigue and oxidative stress in judo athletes: a randomized clinical trial. An Acad Bras Cienc. 2020;92(4):e20191551. https://doi.org/10.1590/0001-3765202020191551.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 58.

    Koli R, Erlund I, Jula A, Marniemi J, Mattila P, Alfthan G. Bioavailability of various polyphenols from a diet containing moderate amounts of berries (dagger). J Agric Food Chem. 2010;58(7):3927–32. https://doi.org/10.1021/jf9024823.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 59.

    Rutledge GA, Fisher DR, Miller MG, Kelly ME, Bielinski DF, Shukitt-Hale B. The effects of blueberry and strawberry serum metabolites on age-related oxidative and inflammatory signaling in vitro. Food Funct. 2019;10(12):7707–13. https://doi.org/10.1039/C9FO01913H.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 60.

    Griñán-Ferré C, Bellver-Sanchis A, Izquierdo V, Corpas R, Roig-Soriano J, Chillón M, et al. The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: from antioxidant to epigenetic therapy. Ageing Res Rev. 2021;67:101271. https://doi.org/10.1016/j.arr.2021.101271.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 61.

    Mykkänen OT, Huotari A, Herzig KH, Dunlop TW, Mykkänen H, Kirjavainen PV. Wild blueberries (Vaccinium myrtillus) alleviate inflammation and hypertension associated with developing obesity in mice fed with a high-fat diet. PLoS One. 2014;9(12):e114790. https://doi.org/10.1371/journal.pone.0114790.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 62.

    Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, et al. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018;556(7701):332–8. https://doi.org/10.1038/s41586-018-0023-4.

    CAS 
    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 63.

    Schwartz M, Ziv Y. Immunity to self and self-maintenance: a unified theory of brain pathologies. Trends Immunol. 2008;29(5):211–9. https://doi.org/10.1016/j.it.2008.01.003.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • 64.

    Carlsen MH, Halvorsen BL, Holte K, Bohn SK, Dragland S, Sampson L, et al. The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide. Nutr J. 2010;9(1):3. https://doi.org/10.1186/1475-2891-9-3.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 65.

    Johansson L, Andersen LF. Who eats 5 a day?: intake of fruits and vegetables among Norwegians in relation to gender and lifestyle. J Am Diet Assoc. 1998;98(6):689–91. https://doi.org/10.1016/S0002-8223(98)00156-4.

    CAS 
    Article 
    PubMed 

    Google Scholar
     

  • [ad_2]

    Source link

    Leave A Comment

    All fields marked with an asterisk (*) are required

    X