Hibiscus and lemon verbena extract show weight management potential: RCT


Monteloeder recently announced that the botanical extract combination found in its Metabolaid ingredient was studied in a randomized, double-blind, placebo-controlled human intervention study on satiety. The study demonstrated that Metabolaid may be an effective tool in increasing satiety effects and reducing food cravings.

The research, published in the European Journal of Nutrition​, demonstrated decreased appetite several hours after a meal, coinciding with increased satiety, and resulting in less food intake for the group supplemented with Metabolaid.

Study details 

The study was conducted on 33 overweight male and female subjects between 18 and 65 years old, with a body mass index (BMI) between 25 and 34.9.

The study was divided into two 60-day periods, separated by a 30-day length wash-out period. At the end of each period, overweight and obese subjects were proposed to eat an ad-libitum meal. Meanwhile, appetite sensation was determined by visual analog scales at different times. Moreover, blood extraction was performed to determine biochemical parameters (lipid and glucidic profile and safety parameters) and to evaluate hunger-related hormones (insulin, leptin, ghrelin, adiponectin, GLP-1 and peptide YY).

The researchers concluded that the group that consumed 500 mg/day of Metabolaid extract for 60 days demonstrated a decrease in appetite sensation, a marked reduction in calorie intake and improved lipidemic profile. Researchers are now developing further studies to more closely examine the variations in hormones and other markers observed in the study.


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